NGC 300 is a fainter member of the Sculptor group of galaxies that includes the more well known NGC 55 and NGC 253. Although the total magnitude is aroound 9, the galaxy is fairly large and so has a rather faint surface brightness. Under very dark skies, it is visible in 50mm binoculars. In an 8" telescope it is easily visible under dark skies as a round, nebulous patch with a slightly brighter centre. The galaxy is situated about 10 degrees north east of the 2nd magnitude star alpha phoenix.
NGC 300 is accessible to northern hemisphere observers, although it does remain rather low. The image below was obtained in central Texas, but even so, the extra atmosphere has taken a toll on the galaxy.