Peer-reviewed Publications

2010
66.
Cannon B, Lewis A, Somerharju P, Virtanen J, Huang J, Cheng KH. (2010) Acyl-chain mismatch driven superlattice arrangement in DPPC/DLPC/Cholesterol Bilayers. J Phys Chem B (accepted for publication).
2009
65.

Qiu L, Lewis A, Como J, Vaughn MW, Huang J, Somerharju P, Virtanen J, Cheng KH. (2009) Cholesterol modulates the Interaction of beta amyloid peptide with lipid bilayers. Biophys J. 96(10): 4299-307. [Abstract]

64.
Vetrova EV, Kudryasheva NS, Cheng KH. (2009) Effect of quinone on the fluorescence decay dynamics of endogenous flavin bound to bacterial luciferase. Biophys Chem 141(1): 59-65. [Abstract]
63.

Somerharju P, Virtanen JA, Cheng KH, Hermansson M. (2009) The superlattice model of lateral organization of membranes and its implications on membrane lipid homeostasis. Biochim Biophys Acta 1788(1): 12-23. [Abstract]

2008
62.
Cheng KH, Aijmo J, Ma L, Yao M, Zhang X, Como J, Hope-Weeks LJ, Huang J, Chen W. (2008) Luminescence Decay Dynamics and Trace Biomaterials Detection Potential of Surface-Functionalized Nanoparticles. J Phys Chem C 112(46): 17931-9. [Abstract]
61.
Cheng KH, Ajimo J, Chen W. (2008) Exploration of functionalized CdTe nanoparticles for latent fingerprint detection. J Nanosci Nanotechnol 8(3): 1170-3. [Abstract]
60.
Liu L, Gill SK, Gao Y, Hope-Weeks LJ, Cheng KH. (2008) Exploration of the use of novel SiO2 nanocomposites doped with fluorescent Eu3+/sensitizer complex for latent fingerprint detection. Forensic Sci Int 176(2-3): 163-72. [Abstract]
2007
59.
Zhu Q, Cheng KH, Vaughn MW. (2007) Molecular dynamics studies of the molecular structure and interactions of cholesterol superlattices and random domains in an unsaturated phosphatidylcholine bilayer membrane. J Phys Chem B 111(37): 11021-31. [Abstract]
58.
Ali MR, Cheng KH, Huang J. (2007) Assess the nature of cholesterol-lipid interactions through the chemical potential of cholesterol in phosphatidylcholine bilayers. Proc Natl Acad Sci U S A 104(13): 5372-7. [Abstract]
57.
Du Z, Cheng KH, Vaughn MW, Collie NL, Gollahon LS. (2007) Recognition and capture of breast cancer cells using an antibody-based platform in a microelectromechanical systems device. Biomed Microdevices 9(1): 35-42. [Abstract]
2006
56.

Ali MR, Cheng KH, Huang J. (2006) Ceramide drives cholesterol out of the ordered lipid bilayer phase into the crystal phase in 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine/cholesterol/ceramide ternary mixtures. Biochemistry 45(41): 12629-38. [Abstract]

55.

Wankhede SP, Du Z, Berg JM, Vaughn MW, Dallas T, Cheng KH, Gollahon L. (2006) Cell detachment model for an antibody-based microfluidic cancer screening system. Biotechnol Prog 22(5): 1426-33. [Abstract]

54.
Cheng KH, Cannon B, Metze J, Lewis A, Huang J, Vaughn MW, Zhu Q, Somerharju P, Virtanen J. (2006) Lipid headgroup superlattice modulates the activity of surface-acting cholesterol oxidase in ternary phospholipid/cholesterol bilayers. Biochemistry 45(36): 10855-64. [Abstract]
53.

Du Z, Colls N, Cheng KH, Vaughn MW, Gollahon L. (2006) Microfluidic-based diagnostics for cervical cancer cells. Biosens Bioelectron 21(10): 1991-5. [Abstract]

52.
Cannon B, Lewis A, Metze J, Thiagarajan V, Vaughn MW, Somerharju P, Virtanen J, Huang J, Cheng KH. (2006) Cholesterol supports headgroup superlattice domain formation in fluid phospholipid/cholesterol bilayers. J Phys Chem B 110(12): 6339-50. [Abstract]
2005
51.
Cannon B, Weaver N, Pu Q, Thiagarajan V, Liu S, Huang J, Vaughn MW, Cheng KH. (2005) Cholesterol modulated antibody binding in supported lipid membranes as determined by total internal reflectance microscopy on a microfabricated high-throughput glass chip. Langmuir 21(21): 9666-74. [Abstract]
50.
Alaoui IM, Menzel ER, Farag M, Cheng KH, Murdock RH. (2005) Mass spectra and time-resolved fluorescence spectroscopy of the reaction product of glycine with 1,2-indanedione in methanol. Forensic Sci Int 152(2-3): 215-9. [Abstract]
2004
49.
Cheng K, Thacker BA, Cardenas RL, Crouch C. (2004) Using an online homework system enhances students' learning of physics concepts in an introductory physics course. Am J Phys 72(11): 1447-53. [Abstract/reprint]
48.
Parker A, Miles K, Cheng KH, Huang J. (2004) Lateral distribution of cholesterol in dioleoylphosphatidylcholine lipid bilayers: cholesterol-phospholipid interactions at high cholesterol limit. Biophys J 86(3): 1532-44. [Abstract]
2003
47.
Cannon B, Heath G, Huang J, Somerharju P, Virtanen JA, Cheng KH. (2003) Time-resolved fluorescence and fourier transform infrared spectroscopic investigations of lateral packing defects and superlattice domains in compositionally uniform cholesterol/phosphatidylcholine bilayers. Biophys J 84(6): 3777-91. [Abstract]
46.
Cannon B, Hermansson M, Gyorke S, Somerharju P, Virtanen JA, Cheng KH. (2003) Regulation of calcium channel activity by lipid domain formation in planar lipid bilayers. Biophys J 85(2): 933-42. [Abstract]
2002
45.
Cardenas RL, Cheng KH, Verhey LJ, Xia P, Davis L, Cannon B. (2002) A self consistent normalized calibration protocol for three dimensional magnetic resonance gel dosimetry. Magn Reson Imaging 20(9): 667-79. [Abstract]
2001
44.
Tanhuanpaa K, Cheng KH, Anttonen K, Virtanen JA, Somerharju P. (2001) Characteristics of pyrene phospholipid/gamma-cyclodextrin complex. Biophys J 81(3): 1501-10. [Abstract]
43.
Cardenas RL, Cheng KH, Sack K. (2001) The effects of cidofovir on progressive multifocal leukoencephalopathy: an MRI case study. Neuroradiology 43(5): 379-82. [Abstract]
2000
42.
Menzel ER, Savoy SM, Ulvick SJ, Cheng KH, Murdock RH, Sudduth MR. (2000) Photoluminescent semiconductor nanocrystals for fingerprint detection. J Forensic Sci 45(3): 545-51. [Abstract]
41.
Menzel ER, Takatsu M, Murdock RH, Bouldin K, Cheng KH. (2000) Photoluminescent CdS/dendrimer nanocomposites for fingerprint detection. J Forensic Sci 45(4): 770-3. [Abstract]
1999
40.
Cheng KH, Virtanen J, Somerharju P. (1999) Fluorescence studies of dehydroergosterol in phosphatidylethanolamine/phosphatidylcholine bilayers. Biophys J 77(6): 3108-19. [Abstract]
39.
Somerharju P, Virtanen JA, Cheng KH. (1999) Lateral organisation of membrane lipids. The superlattice view. Biochim Biophys Acta 1440(1): 32-48. [Abstract]
1998
38.
Virtanen JA, Cheng KH, Somerharju P. (1998) Phospholipid composition of the mammalian red cell membrane can be rationalized by a superlattice model. Proc Natl Acad Sci U S A 95(9): 4964-9. [Abstract]
1997
37.
Cheng KH, Ruonala M, Virtanen J, Somerharju P. (1997) Evidence for superlattice arrangements in fluid phosphatidylcholine/phosphatidylethanolamine bilayers. Biophys J 73(4): 1967-76. [Abstract]
1996
36.
Chen SY, Cheng KH. (1996) Detection of membrane packing defects by time-resolved fluorescence depolarization. Biophys J 71(2): 878-84. [Abstract]
35.
Cheng KH, Somerharju P. (1996) Effects of unsaturation and curvature on the transverse distribution of intramolecular dynamics of dipyrenyl lipids. Biophys J 70(5): 2287-98. [Abstract]
1994
34.
Cheng KH, Somerharju P, Sugar I. (1994) Detection and characterization of the onset of bilayer packing defects by nanosecond-resolved intramolecular excimer fluorescence spectroscopy. Chem Phys Lipids 74(1): 49-64. [Abstract]
33.
Cheng KH. (1994) In vivo tissue characterization of human brain by chisquares parameter maps: multiparameter proton T2-relaxation analysis. Magn Reson Imaging 12(7): 1099-109. [Abstract]
32.
Cheng KH, Ruymgaart L, Liu LI, Somerharju P, Sugar IP. (1994) Intramolecular excimer kinetics of fluorescent dipyrenyl lipids: 2. DOPE/DOPC membranes. Biophys J 67(2): 914-21. [Abstract]
31.
Cheng KH, Ruymgaart L, Liu LI, Somerharju P, Sugar IP. (1994) Intramolecular excimer kinetics of fluorescent dipyrenyl lipids: 1. DMPC/cholesterol membranes. Biophys J 67(2): 902-13. [Abstract]
30.
Cheng KH. (1994) Infrared study of the bilayer stability behavior of binary and ternary phospholipid mixtures containing unsaturated phosphatidylethanolamine. Chem Phys Lipids 70(1): 43-51. [Abstract]
1993
29.
Cheng KH. (1993) Quantitation of non-Einstein diffusion behavior of water in biological tissues by proton MR diffusion imaging: synthetic image calculations. Magn Reson Imaging 11(4): 569-83. [Abstract]
28.
Liu L, Cheng KH, Somerharju P. (1993) Frequency-resolved intramolecular excimer fluorescence study of lipid bilayer and nonbilayer phases. Biophys J 64: 1869-77. [Abstract]
1992
27.
Butko P, Cheng KH. (1992) Activation energy and entropy for intramolecular excimer formation in a dipyrenylphosphatidylcholine probe in lamellar and hexagonal lipid phases. Chem Phys Lipids 62(1): 39-43. [Abstract]
26.
Cheng KH, Hernandez M. (1992) Magnetic resonance diffusion imaging detects structural damage in biological tissues upon hyperthermia. Cancer Res 52(21): 6066-73.[Abstract]
25.
Cheng KH, Lepock JR. (1992) Inactivation of calcium uptake by EGTA is due to an irreversible thermotropic conformational change in the calcium binding domain of the Ca(2+)-ATPase. Biochemistry 31(16): 4074-80. [Abstract]
24.
Chen SY, Cheng KH, Van der Meer BW. (1992) Quantitation of lateral stress in lipid layer containing nonbilayer phase preferring lipids by frequency-domain fluorescence spectroscopy. Biochemistry 31(15): 3759-68. [Abstract]
1991
23.
Cheng KH, Chen SY, Butko P, Van der Meer BW, Somerharju P. (1991) Intramolecular excimer formation of pyrene-labeled lipids in lamellar and inverted hexagonal phases of lipid mixtures containing unsaturated phosphatidylethanolamine. Biophys Chem 39(2): 137-44. [Abstract]
22.
Cheng KH. (1991) Infrared study of the polymorphic phase behavior of dioleoylphosphatidylethanolamine and dioleoylphosphatidylcholine. Chem Phys Lipids 60(2): 119-25. [Abstract]
1990
21.
Chen SY, Cheng KH. (1990) Infrared and time-resolved fluorescencespectroscopic studies of the polymorphic phase behavior of phosphatidylethanolamine/diacylglycerol lipid mixtures. Chem Phys Lipids 56: 149-58. [Abstract]
20.
Chen SY, Cheng KH, Ortalano DM. (1990) Lateral diffusion study of excimer forming lipids in lamellar to inverted hexagonal phase transition of unsaturated phosphatidylethanolamine. Chem Phys Lipids 53(4): 321-9. [Abstract]
19.
Chen SY, Cheng KH, Van der Meer BW, Beechem JM. (1990) Effects of lateral diffusion on the fluorescence anisotropy in hexagonal lipid phases. II. An experimental study. Biophys J 58(6): 1527-37. [Abstract]
18.

Van der Meer BW, Cheng KH, Chen SY. (1990) Effects of lateral diffusion on the fluorescence anisotropy in hexagonal lipid phases. I. Theory. Biophys J 58(6): 1517-26. [Abstract]

17.
Lepock JR, Rodahl AM, Zhang C, Heynen ML, Waters B, Cheng KH. (1990) Thermal denaturation of the Ca2(+)-ATPase of sarcoplasmic reticulum reveals two thermodynamically independent domains. Biochemistry 29(3): 681-9. [Abstract]
16.
Cheng KH. (1990) Headgroup hydration and motional order of lipids in lamellar liquid crystalline and inverted hexagonal phases of unsaturated phosphatidylethanolamine--a time-resolved fluorescence study. Chem Phys Lipids 53(2-3): 191-202. [Abstract]
1989
15.
Cheng KH. (1989) Fluorescence depolarization study on non-bilayer phases of phosphatidylethanolamine and phosphatidylcholine lipid mixtures. Chem Phys Lipids 51(2): 137-45. [Abstract]
14.
Cheng KH. (1989) Fluorescence depolarization study of lamellar liquid crystalline to inverted cylindrical micellar phase transition of phosphatidylethanolamine. Biophys J 55(6): 1025-31. [Abstract]
13.
Cheng KH. (1989) Role of calcium in the thermal inactivation of calcium transport proteins. Cancer Res 49(24 Pt 1): 7026-30. [Abstract]
1987
12.

Cheng KH, Hui SW, Lepock JR. (1987) Protection of the membrane calcium adenosine triphosphatase by cholesterol from thermal inactivation. Cancer Res 47(5): 1255-62. [Abstract]

11.
Lepock JR, Cheng KH, Al-Qysi H, Sim I, Koch CJ, Kruuv J. (1987) Hyperthermia-induced inhibition of respiration and mitochondrial protein denaturation in CHL cells. Int J Hyperthermia 3(2): 123-32. [Abstract]
1986
10.
Legge RL, Cheng KH, Lepock JR, Thompson JE. (1986) Differential Effects of Senescence on the Molecular Organization of Membranes in Ripening Tomato Fruit. Plant Physiol 81(4): 954-9. [Abstract]
9.

Cheng KH, Lepock JR, Hui SW, Yeagle PL. (1986) The role of cholesterol in the activity of reconstituted Ca-ATPase vesicles containing unsaturated phosphatidylethanolamine. J Biol Chem 261(11): 5081-7. [Abstract]

8.
Cheng KH, Hui SW. (1986) Correlation between bilayer destabilization and activity enhancement by diacylglycerols in reconstituted Ca-ATPase vesicles. Arch Biochem Biophys 244(1): 382-6. [Abstract]
1985
7.

Cheng KH, Wiedmer T, Sims PJ. (1985) Fluorescence resonance energy transfer study of the associative state of membrane-bound complexes of complement proteins C5b-8. J Immunol 135(1): 459-64. [Abstract]

6.

Cheng KH, Lepock JR. (1985) Differential polarized phase fluorometric studies of the perturbation of phospholipid packing by BHT. Chem Phys Lipids 37(4): 373-83. [Abstract]

1984
5.
Gruber MY, Cheng KH, Lepock JR, Thompson JE. (1984) Improved yield of plasma membrane from mammalian cells through modifications of the two-phase polymer isolation procedure. Anal Biochem 138(1): 112-8. [Abstract]
1983
4.
Kruuv J, Glofcheski D, Cheng KH, Campbell SD, Al-Qysi HM, Nolan WT, Lepock JR. (1983) Factors influencing survival and growth of mammalian cells exposed to hypothermia. I. Effects of temperature and membrane lipid perturbers. J Cell Physiol 115(2): 179-85. [Abstract]
3.
Lepock JR, Cheng KH, Campbell SD, Kruuv J. (1983) Rotational diffusion of TEMPONE in the cytoplasm of Chinese hamster lung cells. Biophys J 44(3): 405-12. [Abstract]
2.

Lepock JR, Cheng KH, Al-Qysi H, Kruuv J. (1983) Thermotropic lipid and protein transitions in chinese hamster lung cell membranes: relationship to hyperthermic cell killing. Can J Biochem Cell Biol 61(6): 421-7. [Abstract]

1980
1.

Choy CL, Cheng KH, Hsu BS. (1980) Dielectric anisotropy of oriented polychlorotrifluoroethylene. J Polym Sci Phys E 19: 991-1002. [Abstract]